TIAL1 and amebiasis: KEGG data (P<0.05) for up-regulated genes in TIAR KO MEF cells were associated with genes related to focal adhesion, tumorigenesis, cytokine-cytokine receptor interaction, ECM-receptor interaction, amoebiasis, axon guidance, MAPK signalling pathway, endocytosis, protein digestion and absorption, and calcium signalling pathway (Fig. 3C and Fig. S5).