Furthermore, by using GM volume from these 3 brain areas as QT, we performed a GWAS on 74 patients with schizophrenia and 51 controls from a Han Chinese population and identified a number of SNPs from three genes or chromosomal regions (TBXAS1, PIK3C2G and HS3ST5) were associated with changed GM volumes of hOC3vL, vermisL10 and vermisR10. The gene discussed is PIK3C2G; the disease is schizophrenia.