Considering that most Alphabaculoviruses have in their genomes the chiA and v-cath genes, and given the importance of the action of these proteins in the virus-host interaction resulting the insect ́s final liquefaction and further spread of viral progeny, this study proposed to test the hypothesis that the expression of proteins CHIA and V-CATH from CfDefNPV in A. gemmatalis larvae during infection by a recombinant AgMNPV induces liquefaction of the insect tegument and its melanization. This evidence concerns the gene CHIA and infection.