CD4+ T cell numbers were substantially increased in both BAL and lung, and CD8+ T cell number was increased in BAL of RV-immunized vs RV-adjuvant treated mice on day 6 post-infection (p<0.01 BAL and lung CD4+ T cells, p<0.001 BAL CD8+ T cells) (Fig. 2c). Here, CD8A is linked to infection.