In contrast, the dense complex containing CA and IN, as well as viral DNA, was not disrupted by rhTRIM5α during infection with viruses encoding the LNEIE, LMNEIE, INEIE, or NE CA mutants (Figure 6C–F) and only minor differences in the levels of CA, IN, and viral DNA in the dense complex were observed. The gene discussed is CD44; the disease is infection.