Interestingly, the top repressed and downregulated genes are primarily of unknown relevance to infection, though many are receptor or cell surface molecules (Npy6R, Rxfp, Mc2r, Cd200r3, Antxrl, Scara5, Il1r2, Agtr2, GPR165, the olfactory receptor genes, Olfr1314 and Olfr78, and the lectin or lectin-like genes Clec 3b and Reg3A). This evidence concerns the gene REG3A and infection.