MPO and acute respiratory distress syndrome: Here we found that treatment with 2-DG (200 mg/kg i.p. prior to the induction of ventilator-induced ALI) was associated with increased pulmonary edema (Figure 9E), attenuated gas exchange (Figure 9F), enhanced pulmonary neutrophil accumulation as assessed by MPO levels (Figure 9G), and cytokine production (IL-6; Figure 9H).