They included 8 proteins (catalase, tumor rejection antigen/Gp96/, tubulin β, vinculin, peroxiredoxin-2, purine nucleoside phosphorylase, annexin 1 and protein disulfide-isomerase), which simultaneously differentiated healthy bone marrow/blood mononuclear cells from AML M1/M2 mononuclear cells and healthy blood cells from healthy bone marrow. The gene discussed is VCL; the disease is acute myeloid leukemia.