MMP-2 and-9 expression of chondrosarcoma and fibrosarcoma cells treated with IL-1β 10 ng/ml were downregulated by NM treatment in a dose-dependent manner with MMP-2 block at 1000 μg/ml NM and MMP-9 total block at 100 μg/ml NM in fibrosarcoma and at 1000 μg/ml in chondrosarcoma. Here, MMP9 is linked to chondrosarcoma.