Significant negative correlations were found between NM modulation of Matrigel invasion inhibition and MMP-2 secretion with fibrosarcoma HT-1080 (r= −0.911), chondrosarcoma SW-1353 (r= −0.942), liposarcoma SW-872 (r= −0.957) and synovial sarcoma SW-982 (r= −0.878). The gene discussed is MMP2; the disease is liposarcoma.