When the anti-TG2 antibody titer is higher than 10 times ULN, the association with a Marsh 3 lesion is complete, and no other test should be requested; low values of positivity for anti-TG2 are found also in non-CD patients affected by other autoimmune pathologies as well as infections, tumors, myocardial damage, liver disorders, and psoriasis [20, 21]. Here, TGM2 is linked to infection.