ALB and neoplasm: With regard to the intervention mechanism of hMSCs on liver cancer, studies have reported that hMSCs are found to colonize the liver of mouse models of orthotopic liver transplantation, and can differentiate into hepatocytes that express albumin; in addition, the hMSCs are mainly found in the marginal area of the tumor and rarely present in tumors or normal liver tissues, and a large necrotic area is observed in tumor tissues following hMSC transplantation [12].