Ubc9-HA and CacyBP/SIP-3xFLAG were transiently overexpressed in mouse neuroblastoma NB2a cells and proteins from the cell extract were incubated with anti-FLAG M2 affinity resin to isolate CacyBP/SIP-3xFLAG with its targets. This evidence concerns the gene UBE2I and neuroblastoma.