Immunohistochemical staining for cancer markers defined the tumor as positive for vimentin, alpha-1-antitrypsin (AAT), and periodic acid-Schiff (PAS) (Figure 3B, 3C, 3D), but negative for cytokeratin (CK)AE1/AE3, S-100, epithelial membrane antigen (EMA), alpha-smooth muscle actin (SMA), myogeinc differentiation 1 (Myo D1), CK8/18, hepatocyte paraffin 1, human melanoma black-45, melan-A, CD117, synaptophysin, anaplastic lymphoma kinase, CD21, CD35, CD23, and CD34. The gene discussed is VIM; the disease is neoplasm.