These included rs4588 C (P = 0.003, odds ratio [OR]: 0.583, 95% confidence interval [CI]: 0.412–0.836), rs222020 C (P = 0.009, OR: 1.526, 95% CI: 1.117–2.0985), rs2282679 A (P = 0.010, OR: 0.636, 95% CI: 0.449–0.900), and rs2298849 C (P = 0.001, OR: 1.709, 95% CI: 1.250–2.338) in GC, and rs10741657 G (P = 0.019, OR: 1.467, 95% CI: 1.070–2.011) and rs2060793 G (P = 0.023, OR: 0.689, 95% CI: 0.502–0.944) in CYP2R1. The associations of these SNPs with rickets remained significant after adjustment for sex and BMI. This evidence concerns the gene CYP2R1 and rickets.