NRXN1 encodes a neuronal cell surface protein involved in cell recognition and cell adhesion and genome-wide CNV studies have previously implicated NRXN1 deletions in autism and schizophrenia (Ching et al. 2010; Magri et al. 2010) and in AD (Ghani et al. 2012). The gene discussed is NRXN1; the disease is Alzheimer disease.