In the MAPT region at Chr17q21.3, we identified one PD case sample with a large deletion spanning NSF and WNT3. Previously, we identified this region (NSF and WNT3) as a “top hit” in a GWAS study (NSF, rs183211, P = 7.2 × 10−5, OR = 0.54, 95% CI = 0.40–0.73) (Liu et al. 2011). This evidence concerns the gene WNT3 and Parkinson disease.