In this study, we have infected IL-17-/- and wild type (WT) mice with C. muridarum and monitored the clearance of infection, the development of inflammatory pathology (hydrosalpinx) and vaccine-induced protection against both bacterial burden and pathology following IN and transcutaneous immunization (TCI) to determine the requirement for IL-17 during each of these phases of infection. Here, IL17A is linked to infection.