NfL levels in AD (1396 pg/ml, 1139-1711), GBS (1361 pg/ml, 726-2554) and ALS (5513 pg/ml, 4151-7323) were higher than in CP (324 pg/ml, 282-372, p<0.0001 for all), and CSF NfL concentrations in ALS were higher than in AD and GBS (p<0.0001, respectively). Here, NEFL is linked to amyotrophic lateral sclerosis.