KRAS and sarcoma: We next tested the expression of Pint in different mouse cell types at different time points after induction of p53 by doxorubicin-induced DNA damage, including p53+/+ and p53-/- MEFs (Figure 1E), and K-RAS lung tumor and sarcoma cells (Figure 1F,G; see Additional file 1: Figure S2D) after genetic restoration of the p53 gene [23].