ESR1 and neoplasm: The investigators reported that the cumulative probability of survival was positively associated with ER H-score (10-year survival: 41%, 71%, 67%, and 84% for H-scores of >0 to 50, 51 to 100, 101 to 200, and >200, respectively), but found no association with the percentage of tumor cells that had ER-positive nuclei (10-year survival: 65.5%, 43.4%, and 70.9% for the percentage of cells staining for ER of >0 to <34%, 34 to 67%, and >67%, respectively).