Similarly to the effects of hGX in MDA-MB-231 cells, increased rates of β-oxidation associated with AMPK phosphorylation, elevation of CPT1A mRNA and a decrease in lipogenesis due to inactivation of ACC have recently been implicated in the adipocyte-induced survival and metastasis of ovarian cancer cells[60]. The gene discussed is ACACA; the disease is ovarian carcinoma.