Regarding the TNF gene microsatellite, ten alleles were associated with Chagas disease in the Brazilian population: eight of them correlate with susceptibility (TNFa2, TNFa7, TNFa8, TNFb2, TNFb4, TNFd5, TNFd7, and TNFe2) and two with protection (TNFb7 and TNFd3) against the development of the disease [111]. Here, TNF is linked to Chagas disease.