IL1RN and Chagas disease: The IL1B-511(rs16944), IL1F10.3 (rs3811058), IL1RN.4 (rs419598), IL1RN 6/1 (rs315952), and IL-1RN 6/2 (rs315951) polymorphisms were analysed in Chagas disease and IL-1RN.4CC genotype was clearly associated with T. cruzi infection and CCC development [115].