In the first, Tejasvi et al. (2012) evaluated associations between two SNPs in TNFAIP3 (rs2230926 and rs610604) and the response to TNF therapy in a cohort from Michigan (n = 433 patients) and a cohort from Toronto (n = 199 patients), both comprising patients with psoriasis and psoriatic arthritis [15]. The gene discussed is TNFAIP3; the disease is psoriasis.