HMMR and neoplasm: RHAMM, HAS1 and HAS2 mRNA expression levels were significantly increased in higher tumor gradings (G1 versus G2-3; RHAMM, 1.77 fold in low grade, 2.81 fold in high grade tumors, p=0.006; HAS1, 0.02 fold in low grade and 0.26 fold in high grade specimens, p<0.001; HAS2, 0.29 fold in low grade and 0.82 fold in high grade tumors, p=0.014).