HMMR and neoplasm: As a result 45 days after injection of tumor cells reduced tumor size was found in mice that received J82 cells with knock-down of RHAMM compared to the control group (450 mm3 ± 188.2 mm3 for shRHAMM and 711.5 mm3 ± 201.2 mm3 for control, p<0.001, Figure 4 A-C).