IGF1 and neoplasm: As shown in Table 2, fifteen pathways, including Ephrin receptor, ERK/MAPK, HGF, IGF-1, IL-6, IL-8, Integrin linked kinase, Integrin, Neuregulin, p38 MAPK, p53, PI3K/AKT, PPAR, PTEN, and TREM1 were enriched in the both tumor subgroups.