However, when average tumor volumes were analyzed on 29 tumors selected randomly from each of the two groups, a significantly increased tumor size was observed in Tiam1 transgenic mice (Figure 3B and Table 2) with a mean tumor volume (23.260±2.119 mm3) 4.7-fold higher (P<0.001) than in wild-type mice (4.929±0.580 mm3). Here, TIAM1 is linked to neoplasm.