Additionally, we found that those with a WHO III/IV versus I/II (PR: 1.96; 95% CI: 1.81–2.12), patients with a low CD4 count (<50 versus >200 cells/mL; PR: 1.48, 95% CI: 1.28–1.73), and those with tuberculosis at initiation (PR: 1.14, 95% CI 1.06–1.22) were more likely to have anemia at ART initiation. The gene discussed is CD4; the disease is anemia.