Recently, SRSF1 mediated splicing of the MNK2b isoform of the MKNK2 gene has been correlated with resistance to gemcitabine treatment in pancreatic cancer cells [109]; since SRPK1 is upregulated in this cancer type and promotes cell survival, it would be interesting to evaluate whether this kinase contributes to the SRSF1-induced prosurvival pathway. The gene discussed is SRSF1; the disease is familial pancreatic carcinoma.