TGFB1 and cancer: In addition to TGF-β factors secreted by cancer cells that influence stromal fibroblasts include platelet derived growth factor (PDGF; MIM: 173430), interleukin (IL)-6 (MIM:147620), IL1-α (MIM: 147760), and WNT1 inducible signaling pathway protein (WISP)-1 and -2 (MIM: 603398 and 603399) [8], [9].