ERG was furthermore known to be fused with EWSR1 (on 22q12) in a subset of Ewing sarcomas (12,13), and EWSR1 was known to display a high degree of homology with FUS, the 16p11 gene rearranged in the t(12;16)(q13;p11) that characterizes myxoid liposarcomas (14,15). Here, EWSR1 is linked to Ewing sarcoma.