We considered some to be disease causing, as they are the same mutations previously reported in patients with different diseases that accompany autistic features, namely, c.4612G>A (p.V1538I) in SCN1A, identified in a patient with Dravet syndrome [24], and c.878C>T (p.S293F) in SLC6A4, identified in a patient with serotonin transporter deficiency [23]. Here, SLC6A4 is linked to encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.