A number of these genes (n=18) have been previously associated with resistance to chemotherapy in other cancer types (i.e. among others PDCD6, ENDOG, BIRC7, CIRBP, ABCA7, MBD3, TCF3, ORM1, FLNA, NEX6, TUBB3, ABCA2). The gene discussed is TUBB3; the disease is cancer.