According to Rwanda guidelines [13] ART was indicated in HIV patients with TB, but the timing of start of ART depended on the form of TB and the CD4 count (if EPTB or CD4 count <50 cells/mm3 ART should be started 15 days after start TB treatment; if CD4 count 50–200 cells/mm3 start after 2 months, and if CD4 count >200 cells/mm3 the CD4 count should be repeated after 2 months), and also on the assessment of the health care worker that the patient was likely to be adherent to ART. This evidence concerns the gene CD4 and tuberculosis.