One last transcript found in the inactive gonad library was the nuclear receptor subfamily 0 group b member 1, also known as dax-1 (dosage-sensitive sex reversal, adrenal hypoplasia critical region on the X chromosome, gene 1), after the mutant phenotype that causes an X-linked form of adrenal hypoplasia in human males. Here, NR0B1 is linked to chronic primary adrenal insufficiency.