RPGRIP1 and Leber congenital amaurosis: In the LCA chip analysis, 6 of 25 LCA patients revealed potentially disease causing variations in genes GUCY2D, AIPL1, RPGRIP1, CRX and IQCB1. A homozygous missense mutation GUCY2D c.3118C>G (p.R1040G) was identified in two patients (LCA55–1 & LCA87–1).