DNAJB6 and infection: Similar results have been obtained in HCMV-infected cells, where siRNA-mediated knockdown of DNAJB6-a or overexpression of DNAJB6-b prior to infection resulted in dramatically reduced HCMV replication and virus production, while silencing of DNAJB6-b or overexpression of DNAJB6-a causes an increase in HCMV replication and virus production [109]; levels of HCMV replication and virus production correlate well with nuclear accumulation of myc-tagged cotransfected UL70.