Though Metastasis associated lung adenocarcinoma transcript 1 (MALAT-1) is first found abnormal expressed in metastasizing non-small-cell lung carcinomas [6], it is up-regulated in hepatocarcinoma, breast cancer, pancreatic cancer, colorectal cancer, and prostate cancer [7]. The gene discussed is MALAT1; the disease is non-small cell lung carcinoma.