IL1A and atherosclerosis: Association study showed that the TT genotype and T allele of IL-1α-889 C/T were significantly associated with IS of a large artery atherosclerosis (LAA) (TT: OR = 2.01, 95% CI = 1.34–3.0, and P < 0.001; T: OR = 1.44, 95% CI = 1.18–1.78, and P = 0.001).