One hundred eighty-three HIV-positive individuals (45.2%) were negative to all of the serological markers of HBV infection performed in this study, 88 (21.7%) were anti-HBs + anti-HBc positive, 71 (17.5%) showed the serological profile “anti-HBc alone,” and 63 (15.6%) were positive to anti-HBs as unique marker of infection. This evidence concerns the gene KRT88P and infection.