CD40LG and systemic lupus erythematosus: Most studies find no difference between SLE patients and healthy controls in the prevalence of IgG and IgM antibodies to either EBNA1 and VCA [60–63], but studies on pediatric SLE patients and one study on adults show that all SLE patients are seropositive for these antibodies compared to two-thirds of healthy controls [29, 64, 65].