Similarly, D2R receptor blockade by haloperidol induces Fos and Jun B expression during status epilepticus in the hippocampus and striatum (Dragunow et al., 1993); accordingly, KA seizures in D2R-/- mice markedly induce c-fos and c-jun expression (Bozzi et al., 2000; Figure 2). Here, FOS is linked to status epilepticus.