KCNA1 and epilepsy: Electrophysiological investigations from mceph/mceph brain slices revealed hippocampal mceph/mceph brain slices revealed hippocampal hyperexcitability consistent with limbic status epilepticus (SE) C-teminal domain of Kv1.1 channels (R417stop) has also been found in a EA1 proband displaying episodes of ataxia precipitated by exercise, stress, startle or high temperature occurring after a hot bath or when using a hairdryer but, absence of epilepsy (Eunson et al., 2000).