LGI1 mutations—e.g., the point mutation E383A that prevents the neuronal secretion of LGI1—have been found in patients with autosomal dominant lateral temporal lobe epilepsy (ADLTE), a syndrome characterized by partial seizures with acoustic or other sensory hallucinations (Kalachikov et al., 2002; Morante-Redolat et al., 2002; Fukata et al., 2010, Table 1). The gene discussed is LGI1; the disease is autosomal dominant epilepsy with auditory features.