MAP1LC3A and neoplasm: Fluorescent microscopic analysis of the GFP-LC3-expressing metastatic and primary tumor tissues showed that the number of GFP-LC3 dots per area in lung metastases were significantly higher than that in primary HCC tumor (44.31±4.2 vs. 1.95±0.26, P<0.001) (Figure 4B,C,D).