Although TLR2-deficient mice exhibited hepatic levels of TNF-α equivalent to those in WT mice at 6 h post-infection, a subsequent decrease in hepatic TNF-α levels was significantly delayed in TLR2-deficient mice with 7.7-fold higher levels at 3 d post-infection (vs. WT mice; Figure 6A). The gene discussed is TLR2; the disease is infection.