By contrast, lower yields were obtained for the four CML-iPSCs Ph+ (#1.24 and #1.31 from the first CML patient and (#2.1 and #2.2 from the second one), compared to the two Ph- clones: the mean percentages of CD45+ cells generated was equal to 15% for the Ph+ versus 41% for the Ph- clones (p<0.001), 4.2% versus 13.3% (p = 0.006) for the CD34+ cells and 1.2% versus 9.1% for the CD34+/ CD45+ cells (Fig 6B). The gene discussed is PTPRC; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.