Among the numerous proteins that are S-nitrosylated several important regulators of plant defense were identified, including the transcriptional co-regulator NON-EXPRESSOR OF PR1 (NPR1) mediating SA-dependent defense activation (Tada et al., 2008; Lindermayr et al., 2010), the SA-BINDING PROTEIN 3 (SABP3) involved in SA signaling and expression of resistance against pathogen infection (Wang et al., 2009), and the NADPH oxidase RBOHD mediating HR cell death development by synthesis of ROS (Yun et al., 2011). Here, NPR1 is linked to infection.