ALB and impulse control disorder: In order to examine the effect of topically applied rhTRX on ICD, the mice were divided into five groups: (1) a group of mice received rhTRX 2 h before croton oil application (pre-treatment), (2) a group of mice received bovine serum albumin (BSA) 2 h before croton oil application, (3) a group of mice received rhTRX treatment immediately after croton oil application (post-treatment), (4) a group of mice received BSA immediately after croton oil treatment, (5) a group of mice received heat-inactivated rhTRX immediately after croton oil treatment.