Our results showed a 4.5 fold increase of circulating miR-133a levels and an 87 fold increase of plasma cTnI concentrations in CHD patients compared with non-CHD chest pain patients, respectively (Figure 3A and B), and scatter plots on miR-133a levels more clearly illustrated these differences and distribution (Additional file 1: Figure S3C). Here, TNNI3 is linked to coronary artery disorder.