A second validation in an independent set of 39 additional pancreatic cancer cell lines (Additional file 3: Table S6) showed that ALDH1A3 was expressed on average 1,630 fold higher in the tumor cell lines as compared to hTERT-HPNE cells, and 78.5 fold higher in the tumor cell lines as compared to the average of the normal derived tissue samples (Figure 3C). The gene discussed is ALDH1A3; the disease is pancreatic neoplasm.