CAV3 and Duchenne muscular dystrophy: Intriguingly, the fragile muscle fibers from patients with Duchenne muscular dystrophy contain elevated numbers of caveolae-like vesicles (Bonilla et al., 1981; Repetto et al., 1999), and mutations in the muscle-specific caveolar protein caveolin-3 (Cav3) cause multiple forms of muscle pathology (Gazzerro et al., 2010).