The lowest tested dose of Danshen (0.5%) inhibited the serum levels of IgE and inhibited production of NO and generation of protein radicals; it did not affect antibody production, the DTH response, or host defenses against LM. Thus, this relatively low dose might be useful for allergies and asthma, especially in that it did not inhibit protective immune responses. This evidence concerns the gene IGHE and asthma.